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Click here to view a special Pediatric GIST edition of the LRG newsletter!
Click here to view a poster from the NIH Pediatric & Wildtype GIST clinic!
Pediatric GIST: Breaking New Ground
Presenters: Dr. Lee Helman, Director of the Pediatric Oncology Branch of the National Cancer Institute, and Dr. Alberto Pappo, Pediatric Oncologist of Texas Children's Cancer Center
Presented: April 15th, 2008 Duration: 58 minutes
Dr. Lee Helman, the Director of the Pediatric Oncology Branch of the National Cancer Institute, and Dr. Alberto Pappo, Pediatric Oncologist of Texas Children’s Cancer Center, discuss a new initiative for Pediatric GIST patients.
This webcast gives you an opportunity to learn about a new NIH-based clinic scheduled for June 19, 2008. Doctors for the first time in history will come together to explore Pediatric GIST hands-on in hopes of discovering viable treatment options for these patients. Logistics about the event will be discussed by Dr. Helman. Dr. Pappo will present and discuss valuable information about the genetic and clinical elements of Pediatric GIST.
We are honored to have Ashley Young and Jacqui Bromberg, Life Raft Group Pediatric GISTers and Co-chairs for the NIH Clinic Planning Committee, moderating this session (Note: Jacqui was unable to moderate this session but we want to thank her for her continuing dedication in planning the NIH clinic).
♦ Pediatric GIST-Genetic progession mechanisms KIT/PDGFRA transforming roles
2007 Connective Tissue Oncology Society
♦ Gastrointestinal Stromal Tumors in Pediatric Patients MSKCC Grand Rounds
♦ "Pediatric Gastrointestinal Stromal Tumors First NIH Pediatric Wildtype GIST Clinic Presentation, June 18, 2008
♦ Pediatric GIST: KIT inhibitors & IGF1R-directed antibodies
Second NIH Pediatric & Wildtype GIST Clinic Presentation, January 22, 2009
♦ View the NIH Podcast: The 2nd Pediatric GIST Clinic Invitational Lecture-The IGF-1R antibody trial in patients with Pediatric and wildtype GIST
Pediatric GIST - The New (or forgotten) Kid on the Block
Dr. Alberto Pappo
Texas Children's Cancer Center
Dr. Maria Debiec-Rychter
University of Leuven, Belgium
The NIH Pediatric & Wildtype GIST Clinic
2008 Connective Tissue Oncology Society
Dr. Su Young Kim
National Cancer Institute
Clinical and molecular genetics of patients with the Carney-Stratakis syndrome and germline mutations of the genes coding for the succinate dehydrogenase subunits SDHB, SDHC, and SDHD.
Pasini B, McWhinney SR, Bei T, Matyakhina L, Stergiopoulos S, Muchow M, Boikos SA, Ferrando B, Pacak K, Assie G, Baudin E, Chompret A, Ellison JW, Briere JJ, Rustin P, Gimenez-Roqueplo AP, Eng C, Carney JA, Stratakis CA.
Eur J Hum Genet. 2008 Jan;16(1):79-88. Epub 2007 Aug 1.
PMID: 17667967 [PubMed - indexed for MEDLINE]
Related Articles Free article at journal site
Gastrointestinal stromal tumors in children and young adults: a clinicopathologic, molecular, and genomic study of 15 cases and review of the literature.
Prakash S, Sarran L, Socci N, DeMatteo RP, Eisenstat J, Greco AM, Maki RG, Wexler LH, LaQuaglia MP, Besmer P, Antonescu CR.
J Pediatr Hematol Oncol. 2005 Apr;27(4):179-87. Review.
PMID: 15838387 [PubMed - indexed for MEDLINE]
Sunitinib treatment in pediatric patients with advanced GIST following failure of imatinib
Janeway KA, Albritton KH, Van Den Abbeele AD, D'Amato GZ, Pedrazzoli P, Siena S, Picus J, Butrynski JE, Schlemmer M, Heinrich MC, Demetri GD.
Pediatr Blood Cancer. 2009 Mar 26. [Epub ahead of print]
PMID: 19326424 [PubMed - as supplied by publisher]